DOSING

Titrate to target dose to treat moderate to severe B.E.D. IN ADULTS1

Hypothetical patient portrayal. Individual results may vary.

Start with 30 mg per day, the recommended Vyvanse starting dose1

Titrate in increments of 20 mg at approximately weekly intervals from the recommended starting dose of 30 mg/day to achieve the recommended target dose of 50 to 70 mg/day (70 mg/day=max dose).1 Discontinue Vyvanse if binge eating does not improve.

Convenient, once-daily dosing1

Take once daily in the morning with or without food. Avoid afternoon doses because of the potential for insomnia.

Recommended dosing titration1

Check in with your patients regularly to see how Vyvanse is working for them and discontinue Vyvanse if binge eating does not improve.

Dose distribution during the 8-week dose-maintenance period of Study 343*2,3

*Patients were optimized to 50 or 70 mg during a 4-week, dose-optimization period. The doses remained fixed during the 8-week dose-maintenance period.1

Similar dose distributions were seen in the second, identically designed trial.2,3

DOSING SAFETY INFORMATION

  • Severe renal impairment: maximum dose should not exceed 50 mg/day; end stage renal disease: maximum recommended dose of 30 mg/day1
  • Prior to treatment, assess for cardiac disease; after prescribing, keep prescription records, educate patients about abuse, monitor for signs of abuse and overdose, and reevaluate the need for Vyvanse use1

Hypothetical patient portrayal

KEEP IN TOUCH

Stay up to date with the latest information to help support your Vyvanse patients.

References
  1. Vyvanse [package insert]. Lexington, MA: Shire US Inc.
  2. McElroy SL, Hudson J, Ferreira-Cornwell MC, et al. Lisdexamfetamine dimesylate for adults with moderate to severe binge eating disorder: results of two pivotal phase 3 randomized controlled trials. Neuropsychopharmacology. 2016;41(5):1251-1260.
  3. Data on file; SPD489-174; Shire US Inc.

INDICATION AND IMPORTANT SAFETY INFORMATION